Isoviolanthin, CAS 40788-84-9

Product Description: Isoviolanthin, a flavonoid glycoside, could markedly inhibit TGF-β1-mediated migration and invasion by deactivating epithelial-mesenchymal transition (EMT) via the TGF-β/Smad and PI3K/Akt/mTOR pathways in HCC cells. Isoviolanthin exhibits no cytotoxic effects on normal liver LO2 cells[1].

Applications: Cancer-programmed cell death

Formula: C27H30O14

References: [1]Xing S, et al. Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial⁻Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways. Int J Mol Sci. 2018 May 23;19(6).

CAS Number: 40788-84-9

Molecular Weight: 578.52

Compound Purity: 99.66

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: TGF-beta/Smad

• SKU: MEXHY-N6896-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N6896-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK