Product Description: L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].
Applications: COVID-19-immunoregulation
Formula: C4H9NO2S
References: [1]Finkelstein JD, et al. Homocysteine. Int J Biochem Cell Biol. 2000 Apr;32(4):385-9./[2]Leng YP, et al. l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia. Br J Pharmacol. 2018 Apr;175(8):1157-1172.
CAS Number: 6027-13-0
Molecular Weight: 135.18
Compound Purity: 98.0
Research Area: Inflammation/Immunology; Cardiovascular Disease
Solubility: DMSO : < 1 mg/mL/H2O : 25 mg/mL (ultrasonic)
Target: Cathepsin;Endogenous Metabolite
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