L-Sepiapterin, CAS 17094-01-8

Product Description: L-Sepiapterin (Sepiapterin) is a precursor of the endothelial nitric oxide synthase (eNOS) cofactor tetrahydrobiopterin (BH4). L-Sepiapterin improves endothelial dysfunction in small mesenteric arteries from db/db mice, and induces angiogenesis. L-Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression[1][2].

Applications: Cancer-Kinase/protease

Formula: C9H11N5O3

References: [1]Pannirselvam M, et al. Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice. Br J Pharmacol. 2003;140(4):701‐706./[2]Cho YR, et al. Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression. Oncol Rep. 2011;26(4):861‐867.

CAS Number: 17094-01-8

Molecular Weight: 237.22

Compound Purity: 99.50

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• SKU: MEXHY-112234-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-112234-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK