Product Description: L-Stepholidine (Stepholidine) exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C19H21NO4
References: [1]Ma B, et al. L-stepholidine, a natural dopamine receptor D1 agonist and D2 antagonist, inhibits heroin-induced reinstatement. Neurosci Lett. 2014 Jan 24;559:67-71./[2]Zhou M, et al. The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice. Neurotox Res. 2019 Aug;36(2):376-386./[3]Wang W, et al. The effect of L-stepholidine, a novel extract of Chinese herb, on the acquisition, expression, maintenance, and re-acquisition of morphine conditioned place preference in rats. Neuropharmacology. 2007 Feb;52(2):355-61. Epub 2006 Oct 5.
CAS Number: 16562-13-3
Molecular Weight: 327.37
Compound Purity: 99.79
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Dopamine Receptor
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