Product Description: Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development[1].
Applications: COVID-19-anti-virus
Formula: C32H55NO25
References: [1]Gao X, et al. Fucosylated oligosaccharide Lacto-N-fucopentaose I ameliorates enterovirus 71 infection by inhibiting apoptosis. Food Chem X. 2022 Feb 4;13:100244.
CAS Number: 7578-25-8
Molecular Weight: 853.77
Compound Purity: 90.0
Research Area: Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Apoptosis;Bacterial;CDK;Endogenous Metabolite;Enterovirus;Reactive Oxygen Species