Product Description: Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C30H50O
References: [1]Upadhyay A, et al. Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases. Mol Neurobiol. 2018;55(2):1169-1182./[2]Lee S, et al. Lanosterol influences cytoplasmic maturation of pig oocytes in vitro and improves preimplantation development of cloned embryos. Theriogenology. 2016;85(4):575-584.
CAS Number: 79-63-0
Molecular Weight: 426.72
Compound Purity: 98.02
Research Area: Neurological Disease
Solubility: DMSO : 5 mg/mL (ultrasonic)/Ethanol : 3.57 mg/mL (ultrasonic)
Target: Endogenous Metabolite