Leucinostatin A, CAS 76600-38-9

Product Description: Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies[1].

Applications: COVID-19-immunoregulation

Formula: C62H111N11O13

References: [1]Csermely P, et al. The nonapeptide leucinostatin A acts as a weak ionophore and as an immunosuppressant on T lymphocytes. Biochim Biophys Acta. 1994;1221(2):125-132. /[2]Ricci M, et al. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation. Int J Pharm. 2004;275(1-2):61-72. /[3]Brand M, et al. Antiprotozoal Structure-Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action. Angew Chem Int Ed Engl. 2021;60(28):15613-15621.

CAS Number: 76600-38-9

Molecular Weight: 1218.61

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Antibiotic;Fungal

• SKU: MEXHY-P2450-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P2450-0
• Package Unit: Get quote
• Quantity Unit: STK