Leucosceptoside A, CAS 83529-62-8

Product Description: Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM)[1][2][3].

Applications: Metabolism-sugar/lipid metabolism

Formula: C30H38O15

References: [1]Chika Ifeanyi Chukwuma, et al. Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review. J Ethnopharmacol. 2019 May 10;235:329-360./[2]Yan-Yun Li, et al. Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons. Eur J Pharmacol. 2008 Jan 28;579(1-3):134-40./[3]B N Zhou, et al. Phenylethanoid glycosides from Digitalis purpurea and Penstemon linarioides with PKCalpha-inhibitory activity. J Nat Prod. 1998 Nov;61(11):1410-2.

CAS Number: 83529-62-8

Molecular Weight: 638.61

Research Area: Metabolic Disease; Neurological Disease

Solubility: 10 mM in DMSO

Target: Angiotensin-converting Enzyme (ACE);Glucosidase;PKC

• SKU: MEXHY-N8018-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8018-1
• Package Unit: 1 mg
• Quantity Unit: STK