Product Description: Lobelanidine is an antagonist for nicotinic acetylcholine receptor (nAChR), which inhibits α7 nAChR response and α3β2/α3β4 nAChR responses, with IC50 of 2.8 and 8.2 μM[1].
Applications: Neuroscience-Neuromodulation
Formula: C22H29NO2
References: [1]Paz C, et al., (-)-Pentylsedinine, a new alkaloid from the leaves of Lobelia tupa with agonist activity at nicotinic acetylcholine receptor[J]. Natural Product Communications, 2015, 10(8): 1934578X1501000810.
CAS Number: 552-72-7
Molecular Weight: 339.47
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: nAChR