Product Description: Macrocalin B is a diterpenoid, which can be isolated from Isodon xerophilus. Macrocalin B inhibits the proliferation of cancer cells K562, HL-60, A549, MKN, CA and HCT with IC50 of 2.81-171 μM. Macrocalin B inhibits the telomerase in K562 with an IC50 in nanomolar level[1].
Formula: C20H26O6
References: [1]Yang Y, et al., Effects of three diterpenoids on tumour cell proliferation and telomerase activity. Nat Prod Res. 2009;23(11):1007-12.
CAS Number: 93781-75-0
Molecular Weight: 362.42
Research Area: Cancer
Target: Telomerase