Product Description: Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C4H3NO2
References: [1]Renault K, et, al. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Bioconjug Chem. 2018 Aug 15;29(8):2497-2513./[2]Zhang S, et, al. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells. Chem Asian J. 2019 Mar 15;14(6):904-909.
CAS Number: 541-59-3
Molecular Weight: 97.07
Compound Purity: 99.98
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL/H2O : 50 mg/mL (ultrasonic)
Target: ADC Linker