Product Description: Methyl helicterate is a triterpenoid, that can be isolated from Helicteres angustifolia (Sterculiaceae). Methyl helicterate inhibits hepatic stellate cell activation and promotes cell apoptosis through downregulating the ERK1/2 signaling pathway[1][2][3].
Formula: C40H56O6
References: [1]Wei Y, et al. Methyl helicterate inhibits hepatic stellate cell activation through downregulating the ERK1/2 signaling pathway. J Cell Biochem. 2019 Sep;120(9):14936-14945./[2]Huang Q, et al. Effect and mechanism of methyl helicterate isolated from Helicteres angustifolia (Sterculiaceae) on hepatic fibrosis induced by carbon tetrachloride in rats. J Ethnopharmacol. 2012 Oct 11;143(3):889-95./[3]Chen W, et al. Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia. Phytochemistry. 2006 May;67(10):1041-7.
CAS Number: 102637-02-5
Molecular Weight: 632.87
Research Area: Inflammation/Immunology
Target: Apoptosis;ERK
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