Narchinol B, CAS 1356822-09-7

Product Description: Narchinol B (Compound 4) is a sesquiter penoid compound. Narchinol B has anti-inflammatory effects. Narchinol B works by inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins,as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced overproduction of NO in BV2 cells (IC50=2.43 μM)[1].

Formula: C12H16O3

References: [1]Yoon CS, et al. Anti-neuroinflammatory effects of sesquiterpenoids isolated from Nardostachys jatamansi. Bioorg Med Chem Lett. 2018 Jan 15;28(2):140-144.

CAS Number: 1356822-09-7

Molecular Weight: 208.25

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-N8936-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8936-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK