Product Description: Oligomycin B is an antibiotic isolated from marine Streptomyces, used as an eukaryotic ATP synthase inhibitor, induces apoptosis[1][2].
Applications: Neuroscience-Neurodegeneration
Formula: C45H72O12
References: [1]Moerman KL, et al. Evidence that the lichen-derived scabrosin esters target mitochondrial ATP synthase in P388D1 cells. Toxicol Appl Pharmacol. 2003 Aug 1;190(3):232-40./[2]Dame ZT, et al. Oligomycins and pamamycin homologs impair motility and induce lysis of zoospores of the grapevine downy mildew pathogen, Plasmopara viticola. FEMS Microbiol Lett. 2016 Aug;363(16).
CAS Number: 11050-94-5
Molecular Weight: 805.05
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Antibiotic;Apoptosis;ATP Synthase;Bacterial