Product Description: Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Target: Antibacterial; AntiparasiticOrnidazole is a drug that cures some protozoan infections. Ornidazole 1 g/day is effective for the prevention of recurrence of Crohn's disease after ileocolonic resection [1]. Ornidazole is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms [2].
Applications: COVID-19-immunoregulation
Formula: C7H10ClN3O3
References: [1]Rutgeerts, P., et al., Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial. Gastroenterology, 2005. 128(4): p. 856-61./[2]Goldstein, E.J., V.L. Sutter, and S.M. Finegold, Comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and SC-28538. Antimicrob Agents Chemother, 1978. 14(4): p. 609-13.
CAS Number: 16773-42-5
Molecular Weight: 219.63
Compound Purity: 99.58
Research Area: Infection; Cancer
Solubility: DMSO : ≥ 100 mg/mL/H2O : 10 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial;Parasite
English
Deutsch
