Orotidine 5′-monophosphate (trisodium), CAS 68244-58-6

Product Description: Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C10H10N2Na3O11P

References: [1]Subrahmanyeswara Rao NN, et al. QM/MM reveals the sequence of substrate binding during OPRT action. Comput Biol Chem. 2018 Jun;74:31-38.

CAS Number: 68244-58-6

Molecular Weight: 434.14

Compound Purity: 99.86

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: DNA/RNA Synthesis;Endogenous Metabolite

• SKU: MEXHY-N8060A-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8060A-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK