Product Description: Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function[1][2][3].
Applications: Metabolism-sugar/lipid metabolism
Formula: C4H4O5
References: [1]F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33(11): 1757-1770./[2]Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293(51):19932-19941./[3]Li W, et al. Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction. Front Pharmacol. 2022 Oct 13;13:1029775.
CAS Number: 328-42-7
Molecular Weight: 132.07
Compound Purity: 99.88
Research Area: Metabolic Disease
Solubility: DMSO : ≥ 100 mg/mL/H2O : ≥ 100 mg/mL
Target: Endogenous Metabolite;Reactive Oxygen Species