Product Description: Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C18H35NO3
References: [1]Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24./[2]Xu H, et al. N-Palmitoyl glycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome[J]. medRxiv, 2024: 2024.10. 21.24315897./[3]Bradshaw HB, et al. Novel endogenous N-acyl glycines identification and characterization. Vitam Horm. 2009;81:191-205.
CAS Number: 2441-41-0
Molecular Weight: 313.48
Compound Purity: 99.74
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Calcium Channel;NO Synthase
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