Product Description: Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity[1]. Phloracetophenone stimulats bile secretion mediated through Mrp2[2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C8H8O4
References: [1]Charoenteeraboon J, et al. Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. Eur J Pharmacol. 2005 May 16;515(1-3):43-6./[2]Piyachaturawat P, et al. Choleretic activity of phloracetophenone in rats: structure-function studies using acetophenone analogues. Eur J Pharmacol. 2000 Jan 10;387(2):221-7.
CAS Number: 480-66-0
Molecular Weight: 168.15
Compound Purity: 99.98
Research Area: Infection; Metabolic Disease
Solubility: DMSO : 25 mg/mL (ultrasonic)/H2O : 2 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial;Cytochrome P450
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