Phosphoglycolic acid (lithium)

Product Description: Phosphoglycolic acid (lithium) is a competitive inhibitor of phosphoglycerate mutase (PGAM)-B, an enzyme of the glycolytic pathway. Phosphoglycolic acid increases basal and fMLF-induced levels of G6P in intact neutrophils. Phosphoglycolic acid thereby increases upstream intermediates in neutrophils, thereby amplifying the respiratory oxidative burst[1].

Formula: C2H5O6P.xLi

References: [1]Shalom-Barak T, et al. A p21-activated kinase-controlled metabolic switch up-regulates phagocyte NADPH oxidase. J Biol Chem. 2002 Oct 25;277(43):40659-65.

Molecular Weight: 156.03 (free acid)

Compound Purity: 98.0

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Phosphatase

• SKU: MEXHY-138877A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-138877A-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK