Physalin H, CAS 70241-09-7

Product Description: Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively[1].

Formula: C28H31ClO10

References: [1]Arai MA, eta l. Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1-DNA-complex formation. Beilstein J Org Chem. 2014 Jan 13;10:134-40.

CAS Number: 70241-09-7

Molecular Weight: 562.99

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Hedgehog

• SKU: MEXHY-N8270-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8270-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK