Product Description: Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, accumulates in the parenchyma cells of the cotyledons. Phytohemagglutinin is a T-cell activator. Stimulation of human mononuclear leukocytes by Phytohemagglutinin induces the expression of ChAT mRNA, and potentiated ACh synthesis[1].
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]Nagae M, et al. Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold. Glycobiology. 2014;24(4):368-378./[2]Fujii T, et al. Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator. J Neuroimmunol. 1998;82(1):101-107./[3]Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011;10(4):895-903.
CAS Number: 9008-97-3
Molecular Weight: N/A
Compound Purity: 80.0
Research Area: Inflammation/Immunology
Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 10 mg/mL (ultrasonic)
Target: Others
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