Product Description: (-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].
Applications: COVID-19-immunoregulation
Formula: C20H22O6
References: [1]Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46./[2]Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805.
CAS Number: 81446-29-9
Molecular Weight: 358.39
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Apoptosis;Glucosidase