Product Description: Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 μM).
Applications: Cancer-Kinase/protease
Formula: C25H24O6
References: [1]Son IH, et al. Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4753-5./[2]Bajer MM, et al. Characterization of pomiferin triacetate as a novel mTOR and translation inhibitor. Biochem Pharmacol. 2014 Apr 1;88(3):313-21./[3]Bartošíková L, et al. Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats. Interdiscip Toxicol. 2010 Jun;3(2):76-81.
CAS Number: 572-03-2
Molecular Weight: 420.45
Compound Purity: 97.36
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: HDAC;mTOR