Product Description: Pseudocoptisine (Isocoptisine) chloride is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects[1][2].
Applications: COVID-19-immunoregulation
Formula: C19H14ClNO4
References: [1]Hung TM, et al. Anti-amnestic activity of pseudocoptisine from Corydalis Tuber. Biol Pharm Bull. 2008;31(1):159-162./[2]Yun KJ, et al. Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage cells. Int Immunopharmacol. 2009;9(11):1323-1331.
CAS Number: 30044-78-1
Molecular Weight: 355.77
Compound Purity: 99.36
Research Area: Inflammation/Immunology
Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Cholinesterase (ChE)
English
Deutsch
