Product Description: Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].
Applications: COVID-19-immunoregulation
Formula: C22H31Cl2N7O5
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References: [1]Nathans D, et al. Puromycin inhibition of protein synthesis: incorporation of puromycin intopeptide chains. Proc Natl Acad Sci U S A. 1964 Apr;51:585-92./[2]Miyamoto-Sato E, et al. Specific bonding of puromycin to full-length protein at the C-terminus. Nucleic Acids Res. 2000 Mar 1;28(5):1176-82./[3]Schmidt EK, et al. SUnSET, a nonradioactive method to monitor protein synthesis. Nat Methods. 2009 Apr;6(4):275-7.
CAS Number: 58-58-2
Molecular Weight: 544.43
Compound Purity: 99.89
Research Area: Infection
Solubility: DMSO : 50 mg/mL (ultrasonic)/Ethanol : 5 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 50 mg/mL (ultrasonic;warming)/Methanol : 250 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial;Parasite