Product Description: Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP)[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C8H12NO7P
References: [1]Allen GF, et al. Pyridoxal 5'-phosphate deficiency causes a loss of aromatic L-amino acid decarboxylase in patients and human neuroblastoma cells, implications for aromatic L-amino acid decarboxylase and vitamin B(6) deficiency states.J Neurochem. 2010 Jul;114(1):87-96./[2]Calderón-Ospina CA, et al. B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin.CNS Neurosci Ther. 2020 Jan;26(1):5-13.
CAS Number: 41468-25-1
Molecular Weight: 265.16
Compound Purity: 99.38
Research Area: Neurological Disease
Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 5.56 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Endogenous Metabolite
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