Questiomycin A, CAS 1916-59-2

Product Description: Questiomycin A (Phx-3) is a GRP78 (cytoprotective endoplasmic reticulum chaperone) degrader and enhances the anticancer activity of Sorafenib. Questiomycin A is also an antimicrobial/antibiotic that can be obtained from the metabolite of Pseudomonas chlororaphis HT66. Questiomycin A can be used in research on biological control of cancer and plant diseases[1][2].

Formula: C12H8N2O2

References: [1]Machihara K, et al. Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78. Biochem Biophys Res Commun. 2017 Oct 7;492(1):33-40./[2]Guo S, et al. Production of Antibacterial Questiomycin A in Metabolically Engineered Pseudomonas chlororaphis HT66. J Agric Food Chem. 2022 Jun 29;70(25):7742-7750.

CAS Number: 1916-59-2

Molecular Weight: 212.20

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Antibiotic;Bacterial;HSP

• SKU: MEXHY-N8439-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8439-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK