Quinine (hemisulfate hydrate), CAS 207671-44-1

Product Description: Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM[1][2].

Formula: C20H24N2O2.1/2H2O4S.H2O

References: [1]Jane Achan , et al. Quinine, an Old Anti-Malarial Drug in a Modern World: Role in the Treatment of Malaria. Malar J. 2011 May 24;10:144./[2]Wrighton DC, et al. Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium. Br J Pharmacol. 2015 Sep;172(17):4355-63.

CAS Number: 207671-44-1

Molecular Weight: 391.48

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Parasite;Potassium Channel

• SKU: MEXHY-D0143B-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-D0143B-1G
• Package Unit: 1 g
• Quantity Unit: STK