Quinine (sulfate hydrate), CAS 6119-70-6

Product Description: Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM[1][2].

Applications: COVID-19-anti-virus

Formula: C20H24N2O2.1/2H2SO4.2H2O

References: [1]Shilu Malakar，et al. Drug repurposing of quinine as antiviral against dengue virus infection. Virus Res. 2018 Aug 15;255:171-178. doi: 10.1016/j.virusres.2018.07.018. Epub 2018 Jul 25./[2]Jhanwar, Deepika，et al. Chemoprevention of DMBA induced skin carcinogenesis in swiss albino mice by quinine sulfate.(2016): 2636-2640./[3] Ebenezer O Farombi, et al. Quercetin protects against testicular toxicity induced by chronic administration of therapeutic dose of quinine sulfate in rats. J Basic Clin Physiol Pharmacol. 2012 Feb 27;23(1):39-44

CAS Number: 6119-70-6

Molecular Weight: 818.98

Compound Purity: 99.97

Research Area: Others

Solubility: 10 mM in DMSO

Target: Dengue virus;Flavivirus;Parasite;Potassium Channel

• SKU: MEXHY-W010668-50G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W010668-50G
• Green Labware: No
• Package Unit: 50 g
• Quantity Unit: STK