(R)-(+)-O-Demethylbuchenavianine, CAS 1364123-68-1

Product Description: (R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases (CDK). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1, CDK5, glycogen synthase kinase-3 (GSK3), cdc2-like kinase (CLK1) and dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), with IC50s of 1.1, 0.95, >10, >10 and >10 μM, respectively[1].

Applications: Cancer-Kinase/protease

Formula: C21H21NO4

References: [1]Nguyen TB, et al., Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. J Med Chem. 2012 Mar 22;55(6):2811-9.

CAS Number: 1364123-68-1

Molecular Weight: 351.40

Compound Purity: 98.67

Research Area: Cancer

Target: CDK;DYRK;GSK-3

• SKU: MEXHY-N12625-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N12625-1
• Package Unit: 1 mg
• Quantity Unit: STK