Product Description: Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
Formula: C78H124N4O22
References: [1]HIZOPODIN, A NEW COMPOUND FROM Myxococcus stipitatus (MYXOBACTERIA)CAUSES FORMATIONOF RHIZOPODIA-LIKE STRUCTURES IN ANIMAL CELL CULTURES
CAS Number: 150346-23-9
Molecular Weight: 1469.83
Research Area: infection
Target: Others
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