Rubiadin-1-methyl ether, CAS 7460-43-7

Product Description: Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C16H12O4

References: [1]He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931.

CAS Number: 7460-43-7

Molecular Weight: 268.26

Compound Purity: 98.89

Research Area: Metabolic Disease

Solubility: DMSO : ≥ 125 mg/mL

Target: NF-κB

• SKU: MEXHY-N1956-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N1956-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK