Product Description: (S)-(-)-O-Demethylbuchenavianine (Compound (S)-(−)-1) is a flavonoidal alkaloids. (S)-(-)-O-Demethylbuchenavianine is a potent CDK inhibitor, with IC50 values of 0.03 and 0.05 μM for CDK1 and CDK5, respectively[1].
Applications: Cancer-Kinase/protease
Formula: C21H21NO4
References: [1]Nguyen TB, et al. Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. J Med Chem. 2012 Mar 22;55(6):2811-9.
CAS Number: 91147-18-1
Molecular Weight: 351.40
Compound Purity: 96.58
Research Area: Cancer
Target: CDK