SC4453, CAS 59712-21-9

Product Description: SC4453 is a digoxin analogue in which the lactone ring at C17β is replaced by a pyrazine ring. SC4453 is slightly inferior to digoxin in inhibiting (Na+ + K+)-ATPase, but shows similar sensitivity to potassium ions. The differences in the sensitivity of SC4453 to heart and brain tissue from different species are mainly due to differences in its dissociation rate from the receptor. These observations confirm the high sensitivity of the human heart to cardiac glycosides.

Formula: C43H66O15

References: [1]INHIBITION BY DIGOXIN AND SC4453 OF (Na ÷ + K÷)-ATPase PREPARED FROM HUMAN HEART, GUINEA-PIG HEART AND GUINEA-PIG BRAIN

CAS Number: 59712-21-9

Molecular Weight: 822.98

Research Area: Cardiovascular Disease

Target: Na+/K+ ATPase

• SKU: MEXHY-125337-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125337-0
• Package Unit: Get quote
• Quantity Unit: STK