Product Description: Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression[1].
Formula: C40H44O13
References: [1]Pan LL, et al. Shizukaol B, an active sesquiterpene from Chloranthus henryi, attenuates LPS-induced inflammatory responses in BV2 microglial cells. Biomed Pharmacother. 2017 Apr;88:878-884.
CAS Number: 142279-40-1
Molecular Weight: 732.77
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: COX;Interleukin Related;NO Synthase;TNF Receptor