Sibiromycin, CAS 12684-33-2

Product Description: Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine[1][2].

Applications: Cancer-programmed cell death

Formula: C24H33N3O7

References: [1]Gerratana B. Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines. Med Res Rev. 2012;32(2):254-293./[2]Li W, et al. Biosynthesis of sibiromycin, a potent antitumor antibiotic. Appl Environ Microbiol. 2009;75(9):2869-2878.

CAS Number: 12684-33-2

Molecular Weight: 475.53

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Antibiotic;DNA Alkylator/Crosslinker

• SKU: MEXHY-N9460-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N9460-1
• Package Unit: 1 mg
• Quantity Unit: STK