Steffimycin B, CAS 54526-94-2

Product Description: Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).

Applications: COVID-19-immunoregulation

Formula: C29H32O13

References: [1]Trenado-Uribe, et al. Antimycobacterial activity of an anthracycline produced by an endophyte isolated from Amphipterygium adstringens. Mol. Biol. Rep. 45(6), 2563-2570 (2018).

CAS Number: 54526-94-2

Molecular Weight: 588.56

Research Area: Infection

Target: Bacterial

• SKU: MEXHY-N8470-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8470-0
• Package Unit: Get quote
• Quantity Unit: STK