Product Description: Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1].
Applications: COVID-19-immunoregulation
Formula: C19H34O2
References: [1]Lei Zhang, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15(2):169-76./[2]Rafael Peláez, et al. Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. Cells. 2020 Jan 7;9(1):140./[3]Abril Ramírez-Higuera, et al. Preventive Action of Sterculic Oil on Metabolic Syndrome Development on a Fructose-Induced Rat Model. J Med Food. 2020 Mar;23(3):305-311.
CAS Number: 738-87-4
Molecular Weight: 294.47
Compound Purity: 99.0
Research Area: Inflammation/Immunology
Solubility: DMSO : 4.42 mg/mL (ultrasonic)/Ethanol : < 1 mg/mL (ultrasonic)
Target: Stearoyl-CoA Desaturase (SCD)
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