Product Description: Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor with IC50s of 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD4, respectively[1].
Applications: COVID-19-immunoregulation
Formula: C25H22N4O8
References: [1]Dreyton CJ, et al. Insights into the mechanism of Streptonigrin-induced protein arginine deiminase inactivation. Bioorg Med Chem. 2014 Feb 15;22(4):1362-9.
CAS Number: 3930-19-6
Molecular Weight: 506.46
Compound Purity: 99.20
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Protein Arginine Deiminase