Swertiajaponin, CAS 6980-25-2

Product Description: Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1].

Applications: COVID-19-immunoregulation

Formula: C22H22O11

References: [1]Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541.

CAS Number: 6980-25-2

Molecular Weight: 462.40

Compound Purity: 99.84

Research Area: Inflammation/Immunology

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Tyrosinase

• SKU: MEXHY-N2204-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N2204-25
• Package Unit: 25 mg
• Quantity Unit: STK