Product Description: TAN-420E (Dihydroherbimycin A) is an antibiotic, that can be isolated from the fermentation product of Streptomyces hygroscopicus. TAN-420E exhibits cytotoxicity in cancer cells P-388 and KB. TAN-420E scavenges DPPH free radicals with an IC50 of 1.3 μM[1][2].
Formula: C30H44N2O9
References: [1]Lin LZ, et al., 1H-nmr analysis of herbimycins and dihydro-herbimycins. J Nat Prod. 1988 Nov-Dec;51(6):1161-5/[2]Chang HB, et al., Antioxidant properties of dihydroherbimycin A from a newly isolated Streptomyces sp. Biotechnol Lett. 2007 Apr;29(4):599-603.
CAS Number: 91700-93-5
Molecular Weight: 576.68
Research Area: Cancer; Infection
Target: Antibiotic;Reactive Oxygen Species