Product Description: Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
Applications: COVID-19-immunoregulation
Formula: C20H20O7
References: [1]Zhang X, et al. Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. Oncol Rep. 2015 Jul;34(1):302-10./[2]Xu JJ, et al. Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. J Agric Food Chem. 2015 Nov 4;63(43):9520-7./[3]Hagenlocher Y, et al. Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. Eur J Nutr. 2017 Jun;56(4):1609-1620.
CAS Number: 481-53-8
Molecular Weight: 372.37
Compound Purity: 99.27
Research Area: Inflammation/Immunology; Cancer
Solubility: DMSO : 25 mg/mL (ultrasonic)
Target: Apoptosis;Notch
English
Deutsch
