Product Description: Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity[1][1].
Applications: COVID-19-immunoregulation
Formula: C30H48O6
References: [1]Gossan DPA, et, al. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95./[2]Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.
CAS Number: 564-13-6
Molecular Weight: 504.70
Compound Purity: 99.63
Research Area: Infection; Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Bacterial
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