Tetrahydrocortisol, CAS 53-02-1

Product Description: Tetrahydrocortisol is cortisol metabolite. The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase (11β-HSD) activity[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C21H34O5

References: [1]Webster SP, et al. Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™). Br J Pharmacol. 2017 Mar;174(5):396-408./[2]Turpeinen U, et al. Determination of free tetrahydrocortisol and tetrahydrocortisone ratio in urine by liquid chromatography-tandem mass spectrometry. Scand J Clin Lab Invest. 2006;66(2):147-59.

CAS Number: 53-02-1

Molecular Weight: 366.49

Compound Purity: 99.0

Research Area: Metabolic Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Endogenous Metabolite

• SKU: MEXHY-129630-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-129630-10
• Package Unit: 10 mg
• Quantity Unit: STK