Product Description: Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity[1][2]. Xanthoangelol inhibits monoamine oxidases[3]. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[4].
Applications: COVID-19-immunoregulation
Formula: C25H28O4
References: [1]Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28(8) 1404-1407 (2005)./[2]Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring). 2016 Nov;24(11):2351-2360./[3]Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1604-5./[4]Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.
CAS Number: 62949-76-2
Molecular Weight: 392.49
Compound Purity: 99.65
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: AMPK;Apoptosis;Bacterial;Monoamine Oxidase