1,2-Bis(2-iodoethoxy)ethane, CAS 36839-55-1

Product Description: 1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 (HY-122562) and SJF620 (HY-133137). MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively[1].

Applications: Cancer-programmed cell death

Formula: C6H12I2O2

References: [1]Jaime-Figueroa S, et al. Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties. 2020 Feb 1;30(3):126877.

CAS Number: 36839-55-1

Molecular Weight: 369.97

Compound Purity: 98.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PROTAC Linkers

• SKU: MEXHY-133143-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-133143-1G
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK