1-Naphthyl 3,5-dinitrobenzoate, CAS 93261-39-3

Product Description: 1-Naphthyl 3,5-dinitrobenzoate is a potent 5-lipoxygenase inhibitor with IC50 values of 1.04 µM and 3.6 µM for 5-LOX and mPGES-1, respectively. 1-Naphthyl 3,5-dinitrobenzoate has strong inhibition activity in the human whole blood (HWB) assay with an IC50 value of 8.6 μM. 1-Naphthyl 3,5-dinitrobenzoate can be used in research of inflammation[1].

Formula: C17H10N2O6

References: [1]Wu Y, et, al. Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors. J Med Chem. 2012 Mar 22;55(6):2597-605.

CAS Number: 93261-39-3

Molecular Weight: 338.27

Compound Purity: 99.49

Research Area: Inflammation/Immunology

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Lipoxygenase

• SKU: MEXHY-125975-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-125975-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK