2',3'-cGAMP sodium, CAS 2734858-36-5

Description: 2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP sodium binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.

CAS Number: 2734858-36-5

Formula: C20H22N10Na2O13P2

Molecular Weight: 718,37

References: Guo X, et al. Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation. Sci Rep. 2017 Jul 25;7(1):6355.

• SKU: TGMT10065L-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T10065L-5mg
• Package Unit: 5 mg
• Quantity Unit: STK