2-((Azido-PEG8-carbamoyl)methoxy)acetic acid, CAS 846549-37-9

Product Description: 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C22H42N4O12

References: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

CAS Number: 846549-37-9

Molecular Weight: 554.59

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PROTAC Linkers

• SKU: MEXHY-140459-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140459-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK